Epidermis with Atypical Keratinocytes
Be certain they are atypical keratinocytes and not melanocytes , lymphocytes or Paget cells!
If primarily in the lower two thirds of the epidermis then we call these solar keratosis. If full thickness atypia we call these scc in situ.
You may need to do immunoperoxidase studies to determine the true nature of some of these other cells.
There can be clear cell change in keratinocytes due to glycogen in the cells.
